KU-55933
Produktgrößen
5 mg
£163,00
10-1518-5MG
25 mg
£301,00
10-1518-25MG
Über dieses Produkt
- SKU:
- 10-1518
- CAS Number:
- 587871-26-9
- Weitere Details:
- Potent and selective ATM kinase inhibitor IC50s= 13, 2500, 9300, 16600, >100000 and >100000 nM for ATM, DNA-PK, mTOR, PI 3-kinase, PI 4-K and ATR respectively.1 Decreases viability of MCF-7, A549 and HCT116 cells and decreases p21CIP1 levels in vitro.2 Disruption of ATM signaling in primary A-T fibroblasts leads to dysregulation of ribonucleotide reductase and increase resistance to inhibitors of mitochondrial respiration and translation.3 Sensitizes radio-resistant cancer cells.4 Provides neuroprotection against H2O2-induced cell damage.5
- Immunogen:
- Kinase
- Molekulargewicht:
- 395.50
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors