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5 mg
£158,00
10-1502-5MG
25 mg
£281,00
10-1502-25MG
Über dieses Produkt
SKU:
10-1502
CAS Number:
443794-40-9
Weitere Details:
A novel potent inhibitor of poly(ADP-ribose) glycohydrolase (PARG), IC50=1.7 uM1. Pre or post ischemia treatment (40 mg/kg) with GPI-16552 reduces brain infarct volumes in a rat model of cerebral ischemia2. It modulates the inflammatory response to ischemia/reperfusion in a rat splanchnic artery occlusion model3 and reduces the degree of spinal cord inflammation and tissue injury after experimental spinal cord trauma4. Synergizes with temozolomide in decreasing melanoma cell invasion and metastatic spreading in mice injected with B16 melanoma cells5.
Immunogen:
PARP
Molekulargewicht:
502.62
Physischer Zustand:
Solid
Reinheit:
98%
Versandbedingungen:
Ambient
Lagerbedingungen:
RT
Hersteller:
Focus Biomolecules
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
Sell Sheet 1:
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