NSC405020
Produktgrößen
5 mg
£149,00
10-1462-5MG
25 mg
£243,00
10-1462-25MG
Über dieses Produkt
- SKU:
- 10-1462
- CAS Number:
- 7497-07-6
- Weitere Details:
- Membrane type-1 matrix metalloproteinase (MMP14 or MT1-MMP) inhibitor that prevents homodimerization and inhibits MMP14's protumorigenic activity in vivo. (IC50 > 100 uM). Inhibition is via interaction with the hemopexin domain (PEX) of MMP14. NSC-405020 does not interfere with the catalytic activity of MT1-MMP or MMP-2. Suppresses bone erosion in a c-Fos-deficient mouse model.2 Decreases arsenic-mediated invasion of human squamous cell carcinoma HSC5 cells.3
- Immunogen:
- Protease
- Molekulargewicht:
- 260.15
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- RT
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors