K-858
Produktgrößen
5 mg
£158,00
10-1312-5MG
25 mg
£281,00
10-1312-25MG
Über dieses Produkt
- SKU:
- 10-1312
- CAS Number:
- 72926-24-0
- Weitere Details:
- Selective mitotic kinesin Eg5 inhibitor (IC50 = 1.3 uM) which acts in an ATP-noncompetitive manner1,2. It is at least 150-fold more selective for Eg5 than other members of the kinesin superfamily. K858 blocks centrosome separation, activates the spindle checkpoint and induces mitotic arrest accompanied by the formation of monopolar spindles. Displays no effect on microtubule polymerization. Selectively displays antiproliferative effects via induction of mitotic cell death in cancer cells over nontransformed cells1.
- Immunogen:
- Cytoskeleton
- Molekulargewicht:
- 277.35
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- RT
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors