SR-1001
Produktgrößen
5 mg
£174,00
10-1290-5MG
25 mg
£320,00
10-1290-25MG
Über dieses Produkt
- SKU:
- 10-1290
- CAS Number:
- 1335106-03-0
- Weitere Details:
- A high affinity synthetic ligand for both RORA Alpha and RORG Gammat acting as an inverse agonist. It binds specifically to the ligand-binding domain, inducing a conformational change which leads to diminished affinity for co-activators and increased affinity for co-repressors resulting in suppression of transcriptional activity1. It inhibits the development of murine TH17 cells2 and suppresses the expression of cytokines1. Suppresses insulitis and prevents hyperglycemia in a type 1 diabetes mouse model3. Protects against pathologic neovascularization in various mouse models of retinopathy4. Active in vivo
- Immunogen:
- Retinoid receptor and related|Transcription factor
- Molekulargewicht:
- 477.39
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here