Anti-PPM1D Alexa Fluor[R] 647
Produktgrößen
0.1 mg
£312,00
A6-894-0.1MG
Über dieses Produkt
- SKU:
- A6-894
- Anwendung:
- Flow Cytometry, IHC-Paraffin, Immunocytochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 7E11/C5
- Konjugat:
- Alexa Fluor® 647
- Konzentration:
- 0.1 mg/ml
- Weitere Details:
- PPM1D is a Mg2+/Mn2+ dependent protein phosphatase 1D with inducible expression in response to various types of environmental stress. This expression is p53-dependent, and subsequently PPM1D negatively regulates the p53-mediated transcription, thus it suppresses the apoptosis. PPM1D contributes to development of carcinomas, and seems to be a promissing therapeutic target. Amplification of PPM1D is associated with breast cancer.
- Immunogen:
- Purified human PPM1D
- Isotyp:
- IgG1
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody 7E11/C5 recognizes an epitope within the sequence FTNEDELYNLLTDSP of PPM1D, a protein phosphatase, which contributes to development of some carcinomas.
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Exbio
- Typ:
- Antibody
- FluoroFinder: