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Antikörper

Anti-Hu CD209 Alexa Fluor[R] 647

Produktgrößen
100 tests
£312,00
A6-640-100TESTS
Über dieses Produkt
SKU:
A6-640
Anwendung:
Flow Cytometry, Immunocytochemistry
CE/IVD:
RUO
translate.label.attr.clone:
UW60.1
Konjugat:
Alexa Fluor® 647
Weitere Details:
CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).
Immunogen:
CD209-His-tagged fusion protein
Isotyp:
IgG2a
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Spezifität:
The mouse monoclonal antibody UW60.1 recognizes an extracellular epitope of human CD209 (DC-SIGN), a 44 kDa transmembrane receptor, expressed on the surface of dendritic cells and macrophages.
Lagerbedingungen:
2-8[o]C Do not freeze. Protect from light.
Hersteller:
Exbio
Typ:
Antibody
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