Anti-SOS Alexa Fluor[R] 647
Produktgrößen
0.1 mg
£361,00
A6-522-0.1MG
Über dieses Produkt
- SKU:
- A6-522
- Anwendung:
- Immunocytochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- SOS-01
- Konjugat:
- Alexa Fluor® 647
- Konzentration:
- 0.1 mg/ml
- Weitere Details:
- The guanine nucleotide exchange factor Sos (son-of-sevenless) is a complex multidomain protein that activates the small GTPase Ras (H-Ras, K-Ras, N-Ras, but not functionally distinct R-Ras) in response to receptor tyrosine kinase stimulation. Nucleotide exchange activity of Sos is stimulated by allosteric Ras binding. By another (separable) guanine exchange factor domain domain Sos modulates activity of Rac/Rho GTPases. Sos thus integrates signals that affect both gene expression and cytoskeletal reorganization; the Sos-mediated Ras-activation and Rac activation differ in composition and stability of the formed complex.
- Immunogen:
- Peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human Sos protein.
- Isotyp:
- IgG1
- Reaktivitäten:
- Human, Mouse, Non-human Primate
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The antibody SOS-01 reacts with human Sos, an ubiquitously expressed 150 kDa intracellular protein. The epitope sequence is highly conserved and reactivity with multiple species is expected.
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Exbio
- Typ:
- Antibody
- FluoroFinder: