Anti-Hu CD54 Alexa Fluor[R] 647
Produktgrößen
100 tests
£312,00
A6-429-100TESTS
Über dieses Produkt
- SKU:
- A6-429
- Anwendung:
- Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunocytochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 1H4
- Konjugat:
- Alexa Fluor® 647
- Weitere Details:
- CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
- Immunogen:
- Raji cells and spleen cells fused with NS1 cells
- Isotyp:
- IgG2b
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The antibody 1H4 recognizes an extracellular epitope of CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus) expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells; the expression of CD54 is upregulated by activation.
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Exbio
- Typ:
- Antibody
- FluoroFinder: