Anti-FoxP3 Alexa Fluor[R] 488
Produktgrößen
0.025 mg
£231,00
A4-601-0.025MG
0.1 mg
£422,00
A4-601-0.1MG
Über dieses Produkt
- SKU:
- A4-601
- Anwendung:
- Flow Cytometry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 3G3
- Konjugat:
- Alexa Fluor® 488
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- FoxP3 (forkhead box protein 3), a highly conserved forkhead/winged-helix transcription factor, plays a crucial role in maintaining immune homeostasis by governing the development and function of regulatory T cells. It is constitutively expressed at high level in CD25+ CD4+ Treg cells and at low level in a CD25- CD4+ Treg cell subset. Defects in gene encoding FoxP3 protein cause the scurfy phenotype in mice, and in human the IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome.
- Immunogen:
- Full-length His-tagged recombinant murine FoxP3
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody 3G3 recognizes N-terminal region of FoxP3, a 47-55 kDa transcription factor (intracellular antigen), which is the master regulator in the development and function of regulatory T cells.
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Exbio
- Typ:
- Antibody
- FluoroFinder: