Anti-Rt CD161 PE
Produktgrößen
0.025 mg
£138,00
1P-657-0.025MG
0.1 mg
£235,00
1P-657-0.1MG
Über dieses Produkt
- SKU:
- 1P-657
- Anwendung:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 10/78
- Konjugat:
- R-PE
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CD161, also known as Nkrp1 (natural killer receptor protein 1) or Klrb1 (killer cell lectin-like receptor subfamily b member 1), is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on rat NK cells, subset of T cells, dendritic cells, and activated monocytes. Although human CD161 is expressed as one isoform, the rat CD161 has three isoforms, referred to as CD161a, b, and c. These proteins contain C-terminal C-type lectin extracellular domain, a transmembrane domain, and N-terminal intracellular domain, which contains ITIM motif, such as CD161b, and displays inhibitory function, or does not contain ITIM motif, thus also not the inhibitory function, such as CD161a.
- Immunogen:
- Splenic cells purified from the LEW rat
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Rat
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody 10/78 recognizes CD161, an approximately 30 kDa type II transmembrane C-type lectin receptor, expressed on the plasma membrane of NK cells, dendritic cells, activated monocytes and a subset of T cells as a disulphide-linked homodimer. A common extracellular epitope on rat CD161a and b isoforms is detected.
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Exbio
- Typ:
- Antibody
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