Anti-Ms CD11b PE
Produktgrößen
0.025 mg
£127,00
1P-595-0.025MG
0.1 mg
£213,00
1P-595-0.1MG
Über dieses Produkt
- SKU:
- 1P-595
- Anwendung:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- M1/70
- Konjugat:
- R-PE
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.
- Immunogen:
- B10 mouse spleen cells enriched for T cells
- Isotyp:
- IgG2b
- Reaktivitäten:
- Human, Mouse, Non-human Primate, Rabbit
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The rat monoclonal antibody M1/70 detects an extracellular epitope of CD11b (integrin alphaM subunit), a type I transmembrane protein mainly expressed on monocytes/macrophages, granulocytes and NK-cells, which associates with CD18 to form Mac-1 integrin that plays important role in cell-cell interactions.
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Exbio
- Typ:
- Antibody
- FluoroFinder: