Anti-Hu CD140a PE
Produktgrößen
25 tests
£159,00
1P-589-25TESTS
100 tests
£278,00
1P-589-100TESTS
Über dieses Produkt
- SKU:
- 1P-589
- Anwendung:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 16A1
- Konjugat:
- R-PE
- Weitere Details:
- CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.
- Immunogen:
- CD140a-transfected NIH 3T3 cells
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody 16A1 recognizes an extracellular epitope of CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Exbio
- Typ:
- Antibody
- FluoroFinder: