Anti-Hu CD137 PE
Produktgrößen
25 tests
£159,00
1P-143-25TESTS
100 tests
£278,00
1P-143-100TESTS
Über dieses Produkt
- SKU:
- 1P-143
- Anwendung:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 4B4-1
- Konjugat:
- R-PE
- Weitere Details:
- CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
- Immunogen:
- Recombinant human CD137 ectodomain
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Human, Non-human Primate
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody 4B4-1 recognizes an extracellular conformational epitope on CD137, an approximately 40 kDa type I transmembrane protein of the TNFR family expressed mainly on activated T cells.
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Exbio
- Typ:
- Antibody
- FluoroFinder: