Anti-Hu CD88 FITC
Produktgrößen
100 tests
£235,00
1F-736-100TESTS
Über dieses Produkt
- SKU:
- 1F-736
- Anwendung:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- S5/1
- Konjugat:
- FITC
- Weitere Details:
- CD88 / C5aR is a G protein-coupled seven membrane-spanning protein serving as a receptor for C5a component of the complement cascade, and is expressed mainly by monocytes, macrophages, neutrophils, eosinophils, and mast cells, but also e.g. by hepatocytes, glial cells, vascular endothelial cells, or cardiomyocytes. The binding of C5a to CD88 is associated with inflammatory response, including superoxide anion production, chemotaxis, and increased production of acute phase proteins. Expression of CD88 on synovial mast cells and their C5a-mediated degranulation plays a role in pathogenesis of rheumatoid arthritis.
- Immunogen:
- Recombinant N-terminal peptide (Asp15-Asp27) of human C5aR
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Bovine, Human, Other Mammal, Rabbit
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody S5/1 recognizes an extracellular epitope of CD88 protein, a 43 kDa receptor of C5a component of the complement cascade.
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Exbio
- Typ:
- Antibody
- FluoroFinder: