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Antikörper

Anti-Hu CD231 FITC

Produktgrößen
100 tests
£235,00
1F-200-100TESTS
Über dieses Produkt
SKU:
1F-200
Anwendung:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
B2D
Konjugat:
FITC
Weitere Details:
CD231 (TALLA-1, T-ALL-asociated antigen 1), also known as tetraspanin 7, is a 150 kDa (under reducing conditions 32-45 kDa) transmembrane glycoprotein of tetraspanin family, expressed in T-type acute lymphoblastic leukemia, neuroblastoma, and neuronal tissue. Mutations of CD231 gene are associated with X-linked mental retardation, Huntington's chorea, and myotonic dystrophy. CD231 interacts with integrins and may have a role in the control of neurite outgrowth. Antibodies to CD231 are important for detection of T-ALL and are potential targets of its treatment.
Immunogen:
Human T-ALL cell line THP-6
Isotyp:
IgG1
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Spezifität:
The mouse monoclonal antibody B2D recognizes an extracellular epitope of CD231 (TALLA-1, tetraspanin 7), a transmembrane glycoprotein expressed in neuronal tissue and T-ALL.
Lagerbedingungen:
2-8[o]C Do not freeze. Protect from light.
Hersteller:
Exbio
Typ:
Antibody
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