Anti-Hu CD34 Biotin
Produktgrößen
0.1 mg
£235,00
1B-566-0.1MG
Über dieses Produkt
- SKU:
- 1B-566
- Anwendung:
- Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- QBEnd-10
- Konjugat:
- Biotin
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.
- Immunogen:
- Human endothelial vesicles
- Isotyp:
- IgG1
- Reaktivitäten:
- Human, Non-human Primate
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The antibody QBEnd-10 reacts with an extracellular class II epitope on CD34, a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells; it is gradually lost on progenitor cells. This antibody has been also used as an endothelial marker.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody