Anti-Hu CD19 APC
Produktgrößen
25 tests
£159,00
1A-663-25TESTS
100 tests
£278,00
1A-663-100TESTS
Über dieses Produkt
- SKU:
- 1A-663
- Anwendung:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 4G7
- Konjugat:
- APC
- Weitere Details:
- CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
- Immunogen:
- Human CCL (chronic lymphocytic leukemia) cells
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody 4G7 recognizes an extracellular epitope of human CD19.
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Exbio
- Typ:
- Antibody
- FluoroFinder: