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Antikörper

Anti-Hu CD39 APC

Produktgrößen
100 tests
£278,00
1A-184-100TESTS
Über dieses Produkt
SKU:
1A-184
Anwendung:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
TU66
Konjugat:
APC
Weitere Details:
CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), is a cell surface enzyme (with intracellular N- and C-terminus) which hydrolyzes extracellular ATP and ADP to AMP. Inhibition of its enzymatic activity may confer anticancer benefits. The formation of oligomers in the plasma membrane is essential for enzyme activity. It is expressed on Treg cells, and in other cell types, such as mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets. Hydrolysis of ATP and ADP inhibits inflammatory and thrombotic responses. In the nervous system, it regulates purinergic neurotransmission.
Isotyp:
IgG2b, kappa
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Spezifität:
The mouse monoclonal antibody TU66, also known as TU66, recognizes an extracellular epitope of CD39, a 78 kDa cell surface enzyme expressed by regulatory T cells, mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets.
Lagerbedingungen:
2-8[o]C Do not freeze. Protect from light.
Hersteller:
Exbio
Typ:
Antibody
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