Anti-Ms CD45R Purified Low Endotoxin
Produktgrößen
0.025 mg
£78,00
12-715-0.025MG
0.1 mg
£116,00
12-715-0.1MG
Über dieses Produkt
- SKU:
- 12-715
- Anwendung:
- Cell-based/Functional Assay, Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- RA3-6B2
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD45R, also known as B220, is a receptor-type protein tyrosine phosphatase glycoprotein. It is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45R expression also identifies a subset of murine bone marrow cells able to form osteoclast-like cells.
- Immunogen:
- Abelson murine leukemia virus-induced pre-B tumor cells
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Feline, Human, Mouse
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The rat monoclonal antibody RA3-6B2 recognizes an extracellular epitope on CD45R, which is expressed at all developmental stages of B cells, including activated B cells, but also on subsets of NK and T cells. T cells detected by this antibody are supposed to be in activated state.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody