Anti-Hu CD96 Purified
Produktgrößen
0.1 mg
£192,00
11-852-0.1MG
Über dieses Produkt
- SKU:
- 11-852
- Anwendung:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- NK92.39
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD96 is a 160-240 kDa type I transmembrane glycoprotein with intracellular ITIM-like domain, however, without observed inhibitory function. This protein is involved in adhesive interactions of T and NK cells during the late phase of the immune response, and are expressed above all upon their activation. Strong interaction between CD96 and CD155 (poliovirus receptor) stimulates cytotoxicity of activated NK cells, which may play a role in NK cell recognition and killing of CD155-expressing tumor cells. CD96 is expressed on approximately 80% of T cell leukemias and 30% of acute myeloid leukemias and is being used for their immunophenotyping.
- Immunogen:
- human NK92 cell line
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody NK92.39 recognizes an extracellular epitope of CD96, a transmembrane glycoprotein expressed at low levels on resting, and at high levels on activated T and NK cells, as well as on many T cell leukemias.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody