Anti-Hu CD146 Purified
Produktgrößen
0.025 mg
£111,00
11-783-0.025MG
0.1 mg
£181,00
11-783-0.1MG
Über dieses Produkt
- SKU:
- 11-783
- Anwendung:
- Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- P1H12
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD146, also known as MCAM (melanoma cell adhesion molecule) or MUC18, is a heavily glycosylated transmembrane glycoprotein with more than 50% of the mass from carbohydrates. It is expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, activated T cells and activated keratinocytes, and on some cancer cells, especially melanoma. The presence of CD146 on circulating blood cells has been confined to the activated T cells rather than circulating endothelial cells. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration.
- Immunogen:
- cultured human umbilical cells
- Isotyp:
- IgG1
- Reaktivitäten:
- Canine, Human, Mouse, Rabbit
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody P1H12 recognizes an extracellular epitope of CD146, a 118 kDa transmembrane glycoprotein expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, melanoma cells, activated T cells and activated keratinocytes.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody