Anti-Hu CD266 Purified
Produktgrößen
0.025 mg
£111,00
11-755-0.025MG
0.1 mg
£181,00
11-755-0.1MG
Über dieses Produkt
- SKU:
- 11-755
- Anwendung:
- Flow Cytometry, IHC-Frozen, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- ITEM-4
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD266 / TWEAK R (TNFRSF12A), also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK, the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells, as well as on some cancer tissues, and plays a role in CD255-induced endothelial cell migration, proliferation, and angiogenesis. The CD255-CD266 interaction, or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells), which might have therapeutic potential.
- Immunogen:
- human CD266-transfected P815 cells
- Isotyp:
- IgG2b
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody ITEM-4 recognizes an extracellular epitope of CD266 / TWEAK R, a TNFR superfamily receptor for CD255 / TWEAK, a TNF-like weak inducer of apoptosis.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody