Anti-Ms CD105 Purified
Produktgrößen
0.025 mg
£84,00
11-714-0.025MG
0.1 mg
£127,00
11-714-0.1MG
Über dieses Produkt
- SKU:
- 11-714
- Anwendung:
- Flow Cytometry, IHC-Frozen, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- MJ7/18
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD105 (endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.
- Immunogen:
- Inflamed mouse skin
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The rat monoclonal antibody MJ7/18 reacts with an extracellular epitope of CD105 (Endoglin), a 90 kDa type I homodimerizing membrane glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marr
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody