Anti-Hu CD209 Purified
Produktgrößen
0.025 mg
£111,00
11-640-0.025MG
0.1 mg
£181,00
11-640-0.1MG
Über dieses Produkt
- SKU:
- 11-640
- Anwendung:
- Flow Cytometry, Immunocytochemistry, Immunohistochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- UW60.1
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).
- Immunogen:
- CD209-His-tagged fusion protein
- Isotyp:
- IgG2a
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody UW60.1 recognizes an extracellular epitope of human CD209 (DC-SIGN), a 44 kDa transmembrane receptor, expressed on the surface of dendritic cells and macrophages.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody