Anti-ABRA1 Purified
Produktgrößen
0.025 mg
£138,00
11-619-0.025MG
0.1 mg
£235,00
11-619-0.1MG
Über dieses Produkt
- SKU:
- 11-619
- Anwendung:
- Flow Cytometry, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- ABRA1-01
- Konzentration:
- 1 mg/ml
- Weitere Details:
- ABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation.
- Immunogen:
- Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody ABRA1-01 recognizes human ABRA1 (Abraxas, CCDC98), an adaptor protein involved in DNA repair, which migrates as a 45 kDa band on PAAGE under reducing conditions.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody