Anti-Hu CD117 Purified
Produktgrößen
0.025 mg
£111,00
11-586-0.025MG
0.1 mg
£181,00
11-586-0.1MG
Über dieses Produkt
- SKU:
- 11-586
- Anwendung:
- Flow Cytometry, IHC-Frozen, Immunocytochemistry, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 104D2
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.
- Immunogen:
- MOLM-1 megakaryocytic cells
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Bovine, Human, Non-human Primate
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody