Anti-Hu CD261 Purified
Produktgrößen
0.025 mg
£138,00
11-403-0.025MG
0.1 mg
£235,00
11-403-0.1MG
Über dieses Produkt
- SKU:
- 11-403
- Anwendung:
- Flow Cytometry, Immunocytochemistry, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- DR-4-02
- Konzentration:
- 1 mg/ml
- Weitere Details:
- TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).
- Immunogen:
- Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1.
- Isotyp:
- IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody DR-4-02 recognizes an extracellular epitope of TRAIL-R1 (DR4), a human death receptor 4 expressed in most human tissues (spleen, peripheral blood leucocytes, thymus) and in a variety of tumour-derived cell lines.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody