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Antikörper

Anti-Hu CD13 Purified

Produktgrößen
0.025 mg
£116,00
11-396-0.025MG
0.1 mg
£192,00
11-396-0.1MG
Über dieses Produkt
SKU:
11-396
Anwendung:
Flow Cytometry, IHC-Frozen, Immunoprecipitation
CE/IVD:
RUO
translate.label.attr.clone:
WM15
Konzentration:
1 mg/ml
Weitere Details:
CD13 (aminopeptidase N, APN) is a 150 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. This metalloprotease preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 has also role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas.
Immunogen:
Human AML cells
Isotyp:
IgG1
Reaktivitäten:
Human, Non-human Primate
Versandbedingungen:
Blue Ice
Spezifität:
The antibody WM15 recognises an extracellular epitope of human CD13 cell surface glycoprotein, a 150 kDa molecule expressed on granulocytes, endothelial cells, epithelial cells and myeloid progenitors.
Lagerbedingungen:
2-8[o]C Do not freeze.
Hersteller:
Exbio
Typ:
Antibody