Anti-NTAL Purified
Produktgrößen
0.025 mg
£138,00
11-374-0.025MG
0.1 mg
£235,00
11-374-0.1MG
Über dieses Produkt
- SKU:
- 11-374
- Anwendung:
- Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- NAP-07
- Konzentration:
- 1 mg/ml
- Weitere Details:
- NTAL (non-T cell activation linker), also known as LAB (linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
- Immunogen:
- Recombinant cytoplasmic domain (aa 91-243) of human NTAL.
- Isotyp:
- IgG1
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The antibody NAP-07 reacts with an intracellular epitope of Non-T cell activation linker (NTAL), also known as LAB (linker of activated B cells), a 25 - 30 kDa transmembrane adaptor protein associating with lipid raft components in the plasma membrane of B lymphocytes, NK cells and myeloid cells.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody