Anti-Hu CD59 Purified
Produktgrößen
0.025 mg
£111,00
11-234-0.025MG
0.1 mg
£181,00
11-234-0.1MG
Über dieses Produkt
- SKU:
- 11-234
- Anwendung:
- Flow Cytometry, IHC-Paraffin, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- MEM-43/5
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD59 (protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.
- Immunogen:
- Thymocytes and T lymphocytes
- Isotyp:
- IgG2b
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The antibody MEM-43/5 reacts with well defined epitope (around L33) on CD59 (Protectin), a 18-20 kDa glycosylphosphatidylinositol (GPI)-anchored extracellular glycoprotein expressed on the surface of all hematopoietic cells; it is widely present on cells in all tissues. The MEM-43/5 does not compete with most other CD59 antibodies.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody