Anti-Hu CD54 Purified
Produktgrößen
0.025 mg
£111,00
11-228-0.025MG
0.1 mg
£181,00
11-228-0.1MG
Über dieses Produkt
- SKU:
- 11-228
- Anwendung:
- ELISA, Flow Cytometry, IHC-Paraffin, Immunocytochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- MEM-111
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
- Immunogen:
- Raji human Burkitt's lymphoma cell line
- Isotyp:
- IgG2a
- Reaktivitäten:
- Bovine, Human, Rat
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The antibody MEM-111 reacts with an extracellular epitope of CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus). The expression of CD54 is upregulated by activation; it is expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody