Anti-Hu CD273 Purified
Produktgrößen
0.025 mg
£111,00
11-178-0.025MG
0.1 mg
£181,00
11-178-0.1MG
Über dieses Produkt
- SKU:
- 11-178
- Anwendung:
- Flow Cytometry, Immunohistochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 24F.10C12
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD273 / PD-L2 (programmed death ligand-1), also known as B7-DC, is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells, and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279, it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.
- Immunogen:
- human CD273 cDNA
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC), a 25 kDa type I transmembrane protein expressed by dendritic cells, activated monocytes and T cells, heart, first trimester placenta, lung and liver, as well as in Hodgkin's lymphoma cells and primary mediastinal B cell lymphoma (PMBL).
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody