Anti-Hu CD150 Purified Azide Free
Produktgrößen
0.025 mg
£111,00
10-660-0.025MG
0.1 mg
£181,00
10-660-0.1MG
Über dieses Produkt
- SKU:
- 10-660
- Anwendung:
- Flow Cytometry, Immunocytochemistry, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- SLAM.4
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.
- Immunogen:
- Human CD150-transfected 300.19 cells
- Isotyp:
- IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The mouse monoclonal antibody SLAM.4 recognizes an extracellular epitope of CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody