Anti-Ms MHC Class II Purified Azide Free
Produktgrößen
0.1 mg
£170,00
10-621-0.1MG
Über dieses Produkt
- SKU:
- 10-621
- Anwendung:
- Cell-based/Functional Assay, Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- M5/114
- Konzentration:
- 1 mg/ml
- Weitere Details:
- MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.
- Immunogen:
- Activated C57BL/6 mouse spleen cells
- Isotyp:
- IgG2b
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Spezifität:
- The rat monoclonal antibody M5/114 reacts with murine MHC class II glycoproteins. It recognizes a shared extracellular determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Exbio
- Typ:
- Antibody