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Antikörper

NR0B2 rabbit pAb

Produktgrößen
50UL
£ POA
ES9945-50UL
100UL
£ POA
ES9945-100UL
Über dieses Produkt
SKU:
ES9945
Anwendung:
Western Blot, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family; a group of transcription factors regulated by small hydrophobic hormones; a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors; inhibiting their ligand-dependent transcriptional activation. In addition; interaction with estrogen receptors has been demonstrated; leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq; Jul 2008];
Immunogen:
Synthesized peptide derived from human protein . at AA range: 30-110
Isotyp:
IgG
Reaktivitäten:
Human, Rat, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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