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Antikörper

ABCC8 rabbit pAb

Produktgrößen
50UL
£ POA
ES9430-50UL
100UL
£ POA
ES9430-100UL
Über dieses Produkt
SKU:
ES9430
Anwendung:
Western Blot, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1; MDR/TAP; MRP; ALD; OABP; GCN20; White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy; an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II; an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for
Immunogen:
Synthesized peptide derived from human protein . at AA range: 500-580
Isotyp:
IgG
Reaktivitäten:
Human, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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