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Antikörper

DMD rabbit pAb

Produktgrößen
50UL
£ POA
ES9017-50UL
100UL
£ POA
ES9017-100UL
Über dieses Produkt
SKU:
ES9017
Anwendung:
Immunohistochemistry, Immunofluorescence
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
dystrophin(DMD) Homo sapiens The dystrophin gene is the largest gene found in nature; measuring 2.4 Mb. The gene was identified through a positional cloning approach; targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive; fatal; X-linked disorder occurring at a frequency of about 1 in 3;500 new-born males. BMD is a milder allelic form. In general; DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations); while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex; containing at least eight independent; tissue-specific promoters and two polyA-addition sites. Furthermore; dystrophin RNA is differentially spliced; producing a range of different transcripts; encoding a large set of protein isoforms. Dystrophin (as enc
Immunogen:
Synthesized peptide derived from part region of human protein
Isotyp:
IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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