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Antikörper

p38 MAPK rabbit pAb

Produktgrößen
50UL
£ POA
ES8901-50UL
100UL
£ POA
ES8901-100UL
Über dieses Produkt
SKU:
ES8901
Zusätzliche Namen:
Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)
Anwendung:
Western Blot, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals; and are involved in a wide variety of cellular processes such as proliferation; differentiation; transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs); or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2; MEF2C; and MAX; cell cycle regulator CDC25B; and tumor suppressor p53; which suggest the roles of this kinase in stress related transcription and cell cycle regulation; as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding d
Immunogen:
Synthesized peptide derived from human p38 MAPK Polyclonal
Isotyp:
IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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