Bob 1 rabbit pAb
Produktgrößen
50UL
£ POA
ES8740-50UL
100UL
£ POA
ES8740-100UL
Über dieses Produkt
- SKU:
- ES8740
- Zusätzliche Namen:
- POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1;BOB-1;OCA-B;OCT-binding factor 1)
- Anwendung:
- Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- disease:A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.;function:Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent; that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.;PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.;similarity:Belongs to the POU2AF1 family.;tissue specificity:B-cell specific.;
- Immunogen:
- Synthetic peptide from human protein at AA range: 201-250
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
