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Antikörper

Perforin 1 rabbit pAb

Produktgrößen
50UL
£ POA
ES8510-50UL
100UL
£ POA
ES8510-100UL
Über dieses Produkt
SKU:
ES8510
Zusätzliche Namen:
Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)
Anwendung:
Western Blot, Immunohistochemistry, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9; this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules; and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2); a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq; Jul 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from the C-terminal region of human PRF1. AA range:451-500
Isotyp:
IgG
Reaktivitäten:
Human, Rat, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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