Caspase-1 rabbit pAb
Produktgrößen
50UL
£ POA
ES8461-50UL
100UL
£ POA
ES8461-100UL
Über dieses Produkt
- SKU:
- ES8461
- Zusätzliche Namen:
- caspase 1; apoptosis-related cysteine peptidase (interleukin 1; beta; convertase)
- Anwendung:
- Immunofluorescence, Western Blot, Immunohistochemistry, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits; large and small; that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1; a cytokine involved in the processes such as inflammation; septic shock; and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq; Mar 2012];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the C-terminal region of human CASP1. AA range:350-400
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
