TRAP230 rabbit pAb
Produktgrößen
50UL
£ POA
ES8147-50UL
100UL
£ POA
ES8147-100UL
Über dieses Produkt
- SKU:
- ES8147
- Zusätzliche Namen:
- MED12; ARC240; CAGH45; HOPA; KIAA0192; TNRC11; TRAP230; Mediator of RNA polymerase II transcription subunit 12; Activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; Mediator complex subunit 12; OPA-containing prote
- Anwendung:
- Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene; mediator complex subunit 12 (MED12); along with MED13; CDK8 kinase; and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome; also known as FG syndrome; and Lujan-Fryns syndrome. [provided by RefSeq; Aug 2009];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MED12. AA range:611-660
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
