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Antikörper

Claudin-8 rabbit pAb

Produktgrößen
50UL
£ POA
ES7949-50UL
100UL
£ POA
ES7949-100UL
Über dieses Produkt
SKU:
ES7949
Zusätzliche Namen:
CLDN8; Claudin-8
Anwendung:
Western Blot, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets; and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule; and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors; and along with claudin-7; is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq; May 2010];
Immunogen:
The antiserum was produced against synthesized peptide derived from human CLDN8. AA range:81-130
Isotyp:
IgG
Reaktivitäten:
Human, Rat, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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