Frizzled-6 rabbit pAb
Produktgrößen
50UL
£ POA
ES7668-50UL
100UL
£ POA
ES7668-100UL
Über dieses Produkt
- SKU:
- ES7668
- Zusätzliche Namen:
- FZD6; Frizzled-6; Fz-6; hFz6
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- frizzled class receptor 6(FZD6) Homo sapiens This gene represents a member of the 'frizzled' gene family; which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide; a cysteine-rich domain in the N-terminal extracellular region; and seven transmembrane domains; but unlike other family members; this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade; thereby inhibiting the processes that trigger oncogenic transformation; cell proliferation; and inhibition of apoptosis. Alternative splicing results in multiple transcript variants; some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq; Aug 2011];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human FZD6. AA range:116-165
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
