TNF-IP 8L2 rabbit pAb
Produktgrößen
50UL
£ POA
ES7586-50UL
100UL
£ POA
ES7586-100UL
Über dieses Produkt
- SKU:
- ES7586
- Zusätzliche Namen:
- TNFAIP8L2; Tumor necrosis factor alpha-induced protein 8-like protein 2; TIPE2; TNF alpha-induced protein 8-like protein 2; TNFAIP8-like protein 2; Inflammation factor protein 20
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- domain:The central region was initially thought to constitute a DED (death effector) domain. However; 3D-structure data reveal a previously uncharacterized fold that is different from the predicted fold of a DED (death effector) domain. It consists of a large; hydrophobic central cavity that is poised for cofactor binding.;function:Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits jun/ap1 and NF-kappa-B activation. Promotes Fas-induced apoptosis.;similarity:Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.;subunit:May interact with CASP8; however; such result is unclear since PubMed:19079267 could not reproduce the interaction with CASP8.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human TNFAIP8L2. AA range:11-60
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
