WASP (phospho Tyr290) rabbit pAb
Produktgrößen
50UL
£ POA
ES7513-50UL
100UL
£ POA
ES7513-100UL
Über dieses Produkt
- SKU:
- ES7513
- Zusätzliche Namen:
- WAS; IMD2; Wiskott-Aldrich syndrome protein; WASp
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure; and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli; and interact with multiple proteins. Recent studies have demonstrated that these proteins; directly or indirectly; associate with the small GTPase; Cdc42; known to regulate formation of actin filaments; and the cytoskeletal organizing complex; Arp2/3. Wiskott-Aldrich syndrome is a rare; inherited; X-linked; recessive disease characterized by immune dysregulation and microthrombocytopenia; and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein; expressed exclusively in hematopoietic cells; which show signalling and cytoskeletal abnormalities in WAS patients. A t
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human WASP around the phosphorylation site of Tyr290. AA range:256-305
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
