THP rabbit pAb
Produktgrößen
50UL
£ POA
ES7477-50UL
100UL
£ POA
ES7477-100UL
Über dieses Produkt
- SKU:
- ES7477
- Zusätzliche Namen:
- UMOD; Uromodulin; Tamm-Horsfall urinary glycoprotein; THP
- Anwendung:
- Western Blot, ELISA, Immunohistochemistry
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2); glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI); and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq; Jul 2013];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human THP. AA range:329-378
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
