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Antikörper

TNF-R1 rabbit pAb

Produktgrößen
50UL
£ POA
ES7404-50UL
100UL
£ POA
ES7404-100UL
Über dieses Produkt
SKU:
ES7404
Zusätzliche Namen:
TNFRSF1A; TNFAR; TNFR1; Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD antigen CD120a
Anwendung:
Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms; respectively; of its ligand; tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation; which plays a role in cell survival; apoptosis; and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor; which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS); characterized by fever; abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by Re
Immunogen:
The antiserum was produced against synthesized peptide derived from human TNF Receptor I. AA range:381-430
Isotyp:
IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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