RPA32 rabbit pAb
Produktgrößen
50UL
£ POA
ES7062-50UL
100UL
£ POA
ES7062-100UL
Über dieses Produkt
- SKU:
- ES7062
- Zusätzliche Namen:
- RPA2; REPA2; RPA32; RPA34; Replication protein A 32 kDa subunit; RP-A p32; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- function:Required for DNA recombination; repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.;PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage; which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA; and by CDC2.;subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.;subunit:Heterotrimer of 70; 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human RFA2. AA range:10-59
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
